HitPredict

Interactor 1: WDR46 (O15213)
WD repeat-containing protein 46 (WD repeat-containing protein BING4)
Gene: WDR46

Interactor 2: DCAF1 (Q9Y4B6)
DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein)
Gene: DCAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 610 Hs			1 1507
+	Hs
		69640 B0UZZ8_HUMAN (1-610): 1.27e-169: 498: 99.84		DCAF1_HUMAN (1-1507): 0: 1958: 100.00
+	Hs
		903605 PRP19_HUMAN (10-474): 4.42e-82: 268: 14.70		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		1281473 PRP19_HUMAN (10-474): 4.42e-82: 268: 14.70		FBXW7_HUMAN (1039-1242): 6.77e-37: 152: 9.64
+	Hs
		792949 LIS1_HUMAN (233-528): 1.17e-68: 230: 10.56		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		903077 WDR5_HUMAN (309-535): 1.07e-51: 183: 14.35		WDR5_HUMAN (923-1244): 5.84e-46: 171: 13.02
+	Hs
		792967 LIS1_HUMAN (233-528): 1.17e-68: 230: 10.56		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		1357321 PRP19_HUMAN (10-474): 4.42e-82: 268: 14.70		PRP19_HUMAN (1068-1205): 4.06e-13: 76: 14.09
+	Hs
		793026 LIS1_HUMAN (233-528): 1.17e-68: 230: 10.56		KTNB1_HUMAN (1066-1211): 2.14e-23: 109: 14.77
+	Hs
		903418 WDR5_HUMAN (309-535): 1.07e-51: 183: 14.35		FBXW7_HUMAN (1039-1242): 6.77e-37: 152: 9.64
+	Hs
		196984 WDR5_HUMAN (309-535): 1.07e-51: 183: 14.35		PRP4_HUMAN (1178-1389): 5.63e-30: 128: 11.74
+	Sp
		999838 TUP11_SCHPO (15-484): 6.55e-70: 239: 12.55		TUP11_SCHPO (967-1127): 1.81e-11: 71: 13.58
+	Hs
		792935 LIS1_HUMAN (233-528): 1.17e-68: 230: 10.56		LIS1_HUMAN (1255-1393): 1.71e-14: 79.5: 10.14
+	Mm
		925836 LIS1_MOUSE (233-528): 8.52e-69: 230: 10.56		LIS1_MOUSE (1255-1393): 1.71e-14: 79.5: 10.14
+	Sp
		999842 TUP11_SCHPO (15-484): 6.55e-70: 239: 12.55		TUP12_SCHPO (967-1124): 2.65e-11: 70.2: 13.84
+	Hs
		903551 WDR5_HUMAN (309-535): 1.07e-51: 183: 14.35		NLE1_HUMAN (972-1164): 2.95e-28: 122: 14.43
+	Hs
		903349 WDR5_HUMAN (309-535): 1.07e-51: 183: 14.35		WDR5B_HUMAN (1207-1379): 3.77e-28: 119: 10.33
+	Hs
		903109 WDR5_HUMAN (309-535): 1.07e-51: 183: 14.35		RACK1_HUMAN (1049-1209): 4.28e-28: 118: 10.86
+	Hs
		1240442 POC1A_HUMAN (105-386): 2.49e-68: 229: 13.79		POC1B_HUMAN (1039-1120): 1.63e-10: 67.5: 12.20