HitPredict

Interactor 1: GP182 (O15218)
G-protein coupled receptor 182
Gene: GPR182

Interactor 2: GCN1 (Q92616)
Stalled ribosome sensor GCN1 (GCN1 eIF-2-alpha kinase activator homolog) (GCN1-like protein 1) (General control of amino-acid synthesis 1-like protein 1) (Translational activator GCN1) (HsGCN1)
Gene: GCN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 404 Hs			1 2671
+	Hs
		723080 OPRM_HUMAN (2-382): 6.04e-76: 242: 20.31		GCN1_HUMAN (1-2671): 0: 2129: 100.00
+	Hs
		598993 FPR1_HUMAN (54-357): 2.05e-24: 104: 26.28		GCN1_HUMAN (1-2671): 0: 2129: 100.00
+	Hs
		91007 P2RY6_HUMAN (49-330): 3.68e-23: 100: 26.87		E1NZA1_HUMAN (1-2671): 0: 2131: 99.96
+	Hs
		171953 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		723279 APJ_HUMAN (34-397): 3.04e-72: 232: 23.48		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		787434 CXCR4_HUMAN (25-343): 3.18e-72: 231: 22.36		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		172095 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		CAND1_HUMAN (1460-2587): 2.11e-22: 108: 13.92
+	Hs
		787471 GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		723340 APJ_HUMAN (34-397): 3.04e-72: 232: 23.48		CAND1_HUMAN (1460-2587): 2.11e-22: 108: 13.92
+	Hs
		172039 GP182_HUMAN (1-404): 1.17e-85: 268: 100.00		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		686654 CCR1_HUMAN (42-364): 1.4e-78: 248: 24.70		CKAP5_HUMAN (953-1968): 8.99e-11: 70.1: 10.33
+	Hs
		723051 OPRM_HUMAN (2-382): 6.04e-76: 242: 20.31		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		429069 ADRB2_HUMAN (23-399): 3.66e-72: 233: 15.70		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		723321 APJ_HUMAN (34-397): 3.04e-72: 232: 23.48		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		1030954 GPR17_HUMAN (1-362): 6.63e-71: 228: 23.72		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24
+	Hs
		127275 P2RY6_HUMAN (49-330): 3.68e-23: 100: 26.87		IPO5_HUMAN (1381-2409): 4.59e-37: 155: 12.18
+	Hs
		598924 FPR1_HUMAN (54-357): 2.05e-24: 104: 26.28		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		672424 P2RY6_HUMAN (49-330): 3.68e-23: 100: 26.87		2AAB_HUMAN (2265-2670): 2.67e-36: 149: 14.67
+	Hs
		787488 P2RY6_HUMAN (49-330): 3.68e-23: 100: 26.87		MTOR_HUMAN (824-2632): 3.31e-34: 147: 12.46
+	Hs
		598959 FPR1_HUMAN (54-357): 2.05e-24: 104: 26.28		ECM29_HUMAN (1769-2544): 4.52e-09: 64.6: 12.24