HitPredict

Interactor 1: MATN3 (O15232)
Matrilin-3
Gene: MATN3

Interactor 2: PDIA1 (P07237)
Protein disulfide-isomerase (PDI) (EC 5.3.4.1) (Cellular thyroid hormone-binding protein) (Prolyl 4-hydroxylase subunit beta) (p55)
Gene: P4HB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	23956175
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005788 - endoplasmic reticulum lumen
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 486 Hs			1 508
+	Hs
		172788 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57
+	Hs
		423214 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00
+	Hs
		423141 TENX_HUMAN (213-486): 3.53e-23: 105: 14.69		PDIA1_HUMAN (1-508): 6.42e-154: 450: 100.00
+	Hs
		566855 ITA2_HUMAN (6-202): 5.24e-39: 153: 21.72		PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57
+	Hs
		671799 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57
+	Hs
		518048 CO6A3_HUMAN (51-239): 4.47e-11: 67.6: 19.42		PDIA3_HUMAN (2-495): 1.97e-121: 367: 31.57
+	Hs
		172782 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22
+	Hs
		172798 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		DJC10_HUMAN (248-481): 6.3e-22: 101: 18.38
+	Hs
		172795 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		PDIA6_HUMAN (372-462): 5.71e-09: 60.1: 36.26
+	Hs
		531805 COEA1_HUMAN (8-264): 2.65e-41: 160: 27.91		PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22
+	Hs
		531812 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22
+	Hs
		1016971 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		DJC10_HUMAN (248-481): 6.3e-22: 101: 18.38
+	Hs
		531962 COCA1_HUMAN (74-264): 7.16e-34: 138: 35.94		PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22
+	Hs
		1067740 VWA1_HUMAN (69-246): 6.63e-38: 145: 30.34		PDIA6_HUMAN (372-462): 5.71e-09: 60.1: 36.26
+	Hs
		1016952 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA6_HUMAN (372-462): 5.71e-09: 60.1: 36.26
+	Hs
		1220494 FBLN5_HUMAN (261-350): 1.97e-11: 67.8: 27.84		DJC10_HUMAN (248-481): 6.3e-22: 101: 18.38
+	Hs
		531747 FBN2_HUMAN (263-430): 4.36e-10: 64.7: 27.81		PDIA4_HUMAN (330-505): 3.94e-23: 104: 22.22
+	Hs
		1220425 LTBP4_HUMAN (205-464): 2.78e-10: 65.2: 15.23		DJC10_HUMAN (248-481): 6.3e-22: 101: 18.38