HitPredict

Interactor 1: MATN3 (O15232)
Matrilin-3
Gene: MATN3

Interactor 2: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	23956175, 16287128
Identification Methods	anti tag coimmunoprecipitation, cross-linking study
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 486 Hs			1 645
+	Hs
		531805 COEA1_HUMAN (8-264): 2.65e-41: 160: 27.91		PDIA4_HUMAN (1-645): 0: 571: 100.00
+	Hs
		531812 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA4_HUMAN (1-645): 0: 571: 100.00
+	Hs
		531962 COCA1_HUMAN (74-264): 7.16e-34: 138: 35.94		PDIA4_HUMAN (1-645): 0: 571: 100.00
+	Hs
		531747 FBN2_HUMAN (263-430): 4.36e-10: 64.7: 27.81		PDIA4_HUMAN (1-645): 0: 571: 100.00
+	Hs
		172798 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47
+	Hs
		172780 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11
+	Hs
		172795 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51
+	Hs
		172788 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35
+	Hs
		1016971 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47
+	Hs
		423214 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11
+	Hs
		1067740 VWA1_HUMAN (69-246): 6.63e-38: 145: 30.34		PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51
+	Hs
		566855 ITA2_HUMAN (6-202): 5.24e-39: 153: 21.72		PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35
+	Hs
		1016952 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA6_HUMAN (57-283): 2.92e-31: 128: 28.51
+	Hs
		1016970 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		Q86UY0_HUMAN (206-510): 2.79e-31: 127: 16.48
+	Hs
		671799 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35
+	Hs
		1016975 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		TXND5_HUMAN (547-631): 1.03e-21: 100: 34.48
+	Hs
		1220494 FBLN5_HUMAN (261-350): 1.97e-11: 67.8: 27.84		DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47
+	Hs
		1220425 LTBP4_HUMAN (205-464): 2.78e-10: 65.2: 15.23		DJC10_HUMAN (41-295): 2.22e-45: 174: 22.47
+	Hs
		423141 TENX_HUMAN (213-486): 3.53e-23: 105: 14.69		PDIA1_HUMAN (4-165): 4.25e-32: 132: 27.11
+	Hs
		518048 CO6A3_HUMAN (51-239): 4.47e-11: 67.6: 19.42		PDIA3_HUMAN (7-188): 4.76e-28: 120: 28.35