HitPredict

Interactor 1: MATN3 (O15232)
Matrilin-3
Gene: MATN3

Interactor 2: PDIA6 (Q15084)
Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7)
Gene: PDIA6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	23956175
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005788 - endoplasmic reticulum lumen
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 486 Hs			1 440
+	Hs
		1067740 VWA1_HUMAN (69-246): 6.63e-38: 145: 30.34		PDIA6_HUMAN (1-440): 1.21e-134: 396: 100.00
+	Hs
		1016952 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA6_HUMAN (1-440): 1.21e-134: 396: 100.00
+	Hs
		172798 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		DJC10_HUMAN (119-381): 3.95e-19: 92.3: 20.68
+	Hs
		172782 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		PDIA4_HUMAN (67-271): 1.28e-17: 87.3: 22.28
+	Hs
		172780 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		PDIA1_HUMAN (62-387): 6.18e-10: 63: 11.59
+	Hs
		172788 MATN3_HUMAN (1-486): 1.79e-97: 304: 100.00		PDIA3_HUMAN (13-386): 9.31e-10: 62.6: 11.02
+	Hs
		1016975 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		TXND5_HUMAN (177-431): 3.21e-41: 153: 20.37
+	Hs
		1016970 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		Q86UY0_HUMAN (190-431): 8.1e-36: 137: 19.46
+	Hs
		531805 COEA1_HUMAN (8-264): 2.65e-41: 160: 27.91		PDIA4_HUMAN (67-271): 1.28e-17: 87.3: 22.28
+	Hs
		1016971 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		DJC10_HUMAN (119-381): 3.95e-19: 92.3: 20.68
+	Hs
		531812 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA4_HUMAN (67-271): 1.28e-17: 87.3: 22.28
+	Hs
		531962 COCA1_HUMAN (74-264): 7.16e-34: 138: 35.94		PDIA4_HUMAN (67-271): 1.28e-17: 87.3: 22.28
+	Hs
		566855 ITA2_HUMAN (6-202): 5.24e-39: 153: 21.72		PDIA3_HUMAN (13-386): 9.31e-10: 62.6: 11.02
+	Hs
		423214 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA1_HUMAN (62-387): 6.18e-10: 63: 11.59
+	Hs
		671799 FBLN3_HUMAN (277-428): 1.42e-36: 142: 27.56		PDIA3_HUMAN (13-386): 9.31e-10: 62.6: 11.02
+	Hs
		423141 TENX_HUMAN (213-486): 3.53e-23: 105: 14.69		PDIA1_HUMAN (62-387): 6.18e-10: 63: 11.59
+	Hs
		1220494 FBLN5_HUMAN (261-350): 1.97e-11: 67.8: 27.84		DJC10_HUMAN (119-381): 3.95e-19: 92.3: 20.68
+	Hs
		1220425 LTBP4_HUMAN (205-464): 2.78e-10: 65.2: 15.23		DJC10_HUMAN (119-381): 3.95e-19: 92.3: 20.68
+	Hs
		531747 FBN2_HUMAN (263-430): 4.36e-10: 64.7: 27.81		PDIA4_HUMAN (67-271): 1.28e-17: 87.3: 22.28
+	Hs
		518048 CO6A3_HUMAN (51-239): 4.47e-11: 67.6: 19.42		PDIA3_HUMAN (13-386): 9.31e-10: 62.6: 11.02