HitPredict

Interactor 1: CASC3 (O15234)
Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz)
Gene: CASC3

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019899 - enzyme binding GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 703 Hs			1 246
+	Hs
		172840 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		172848 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		927045 MDC1_HUMAN (26-703): 5.64e-39: 157: 9.51		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		297821 K0754_HUMAN (50-430): 7.32e-19: 94.2: 9.71		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		297815 K0754_HUMAN (50-430): 7.32e-19: 94.2: 9.71		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		297824 K0754_HUMAN (50-430): 7.32e-19: 94.2: 9.71		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		909862 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683578 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		909712 OTOG_HUMAN (18-409): 3.42e-09: 62.6: 10.93		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		927346 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		683472 OTOG_HUMAN (18-409): 3.42e-09: 62.6: 10.93		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		927196 OTOG_HUMAN (18-409): 3.42e-09: 62.6: 10.93		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		647144 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		647025 OTOG_HUMAN (18-409): 3.42e-09: 62.6: 10.93		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		904919 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		203217 SYNJ1_HUMAN (26-427): 1.45e-09: 63.7: 9.26		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982330 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		904746 OTOG_HUMAN (18-409): 3.42e-09: 62.6: 10.93		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		203222 SYNJ1_HUMAN (26-427): 1.45e-09: 63.7: 9.26		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		684237 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62