HitPredict

Interactor 1: ATX7 (O15265)
Ataxin-7 (Spinocerebellar ataxia type 7 protein)
Gene: ATXN7

Interactor 2: UBP22 (Q9UPT9)
Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22)
Gene: USP22

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.748

The method score is based on:

Property Details
Experiments 26195632, 24981860, 18206972, 21746879, 35271311, 19843541, 18206973
Identification Methods affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000124 - SAGA complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006282 - regulation of DNA repair
GO:0006357 - regulation of transcription by RNA polymerase II
and 3 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 892
Hs

1 525
+ Hs
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+ Sp
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024