Interactor 1: SPTC1 (O15269)
Serine palmitoyltransferase 1 (EC 2.3.1.50) (Long chain base biosynthesis protein 1) (LCB 1) (Serine-palmitoyl-CoA transferase 1) (SPT 1) (SPT1)
Gene: SPTLC1

Interactor 2: ORML3 (Q8N138)
ORM1-like protein 3
Gene: ORMDL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 30529276, 20182505
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Aminotran_1_2~ORMDL
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006686 - sphingomyelin biosynthetic process
GO:0030148 - sphingolipid biosynthetic process
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 473
Hs

1 153
+ Hs
+ Hs
+ At
+ At
+ Sc
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024