Interactor 1: TELT (O15273)
Telethonin (Titin cap protein)
Gene: TCAP

Interactor 2: TITIN (Q8WZ42)
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene: TTN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 9817758, 23414517, 9645487, 9804419, 12446666, 15802564, 16407954, 19622741, 16962094, 15582318, 11846417
Identification Methods two hybrid, pull down, enzymatic study, biochemical, x-ray crystallography, atomic force microscopy, molecular sieving, comigration in non denaturing gel electrophoresis, two hybrid fragment pooling approach
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~Telethonin
Common GO terms GO:0003300 - cardiac muscle hypertrophy
GO:0005829 - cytosol
GO:0008307 - structural constituent of muscle
GO:0030018 - Z disc
GO:0030240 - skeletal muscle thin filament assembly
and 9 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 167
Hs

1 34350
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024