Interactor 1: OGT1 (O15294)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)
Gene: OGT

Interactor 2: TET1 (Q8NFU7)
Methylcytosine dioxygenase TET1 (EC 1.14.11.80) (CXXC-type zinc finger protein 6) (Leukemia-associated protein with a CXXC domain) (Ten-eleven translocation 1 gene protein)
Gene: TET1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 25517638, 27705803, 23353889
Identification Methods affinity chromatography technology, tandem affinity purification, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0006493 - protein O-linked glycosylation
GO:0030336 - negative regulation of cell migration
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1046
Hs

1 2136
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024