HitPredict

Interactor 1: OGT1 (O15294)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)
Gene: OGT

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	32994395
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1046 Hs			1 456
+	Hs
		175312 OGT1_HUMAN (1-1046): 0: 969: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Mm
		888065 CTR9_MOUSE (1-638): 2.38e-48: 189: 14.21		RUVB1_MOUSE (1-456): 0: 704: 99.78
+	Mm
		1143241 CTR9_MOUSE (1-638): 2.38e-48: 189: 14.21		RUVB2_MOUSE (2-455): 0: 651: 42.76
+	Hs
		685119 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		1190247 NPHP3_HUMAN (71-356): 7.12e-10: 65.5: 24.00		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		685116 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		RUVB2_HUMAN (2-455): 0: 651: 42.76