HitPredict

Interactor 1: OGT1 (O15294)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)
Gene: OGT

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	25900982, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0007165 - signal transduction GO:0045862 - positive regulation of proteolysis GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1046 Hs			1 605
+	Hs
		175294 OGT1_HUMAN (1-1046): 0: 969: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		174768 OGT1_HUMAN (1-1046): 0: 969: 100.00		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		174976 OGT1_HUMAN (1-1046): 0: 969: 100.00		TRAF7_HUMAN (416-589): 7.75e-29: 123: 27.12
+	Hs
		175177 OGT1_HUMAN (1-1046): 0: 969: 100.00		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67
+	Hs
		1305141 DNJC7_HUMAN (7-170): 2.97e-17: 88.3: 14.12		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		300222 PRP6_HUMAN (1-275): 6.86e-21: 101: 15.90		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		672800 CDC27_HUMAN (214-530): 4.3e-38: 156: 16.35		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		300095 PRP6_HUMAN (1-275): 6.86e-21: 101: 15.90		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		209396 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		196929 PRP6_HUMAN (1-275): 6.86e-21: 101: 15.90		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Hs
		196960 STIP1_HUMAN (9-183): 1.55e-18: 92.7: 11.43		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Hs
		297048 TOM70_HUMAN (352-634): 3.11e-15: 82.3: 12.06		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33