HitPredict

Interactor 1: RPC7 (O15318)
DNA-directed RNA polymerase III subunit RPC7 (RNA polymerase III subunit C7) (DNA-directed RNA polymerase III subunit G) (RNA polymerase III 32 kDa apha subunit) (RPC32-alpha) (RNA polymerase III 32 kDa subunit) (RPC32)
Gene: POLR3G

Interactor 2: RPC4 (P05423)
DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D) (Protein BN51) (RNA polymerase III 47 kDa subunit) (RPC53 homolog)
Gene: POLR3D

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.747

The method score is based on:

Property Details
Experiments 26186194, 28514442, 12391170, 33961781, 35271311, 20154270, 19631370
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005829 - cytosol
GO:0032728 - positive regulation of interferon-beta production
and 3 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 223
Hs

1 398
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024