Interactor 1: RPC7 (O15318)
DNA-directed RNA polymerase III subunit RPC7 (RNA polymerase III subunit C7) (DNA-directed RNA polymerase III subunit G) (RNA polymerase III 32 kDa apha subunit) (RPC32-alpha) (RNA polymerase III 32 kDa subunit) (RPC32)
Gene: POLR3G

Interactor 2: RPC3 (Q9BUI4)
DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) (RNA polymerase III 62 kDa subunit) (RPC62)
Gene: POLR3C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.965

The method score is based on:

Property Details
Experiments 32296183, 35271311, 9171375, 21358628, 20154270, 19631370, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HTH_9~RNA_pol_3_Rpc31, RNA_pol_3_Rpc31~RNA_pol_Rpc82
Common GO terms GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005829 - cytosol
GO:0006359 - regulation of transcription by RNA polymerase III
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 223
Hs

1 534
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024