Interactor 1: VA0E1 (O15342)
V-type proton ATPase subunit e 1 (V-ATPase subunit e 1) (V-ATPase 9.2 kDa membrane accessory protein) (V-ATPase M9.2 subunit) (Vacuolar proton pump subunit e 1)
Gene: ATP6V0E1

Interactor 2: VPP2 (Q9Y487)
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)
Gene: ATP6V0A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP_synt_H~V_ATPase_I
Common GO terms GO:0005765 - lysosomal membrane
GO:0007035 - vacuolar acidification
GO:0010008 - endosome membrane
GO:0016241 - regulation of macroautophagy
GO:0030670 - phagocytic vesicle membrane
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 81
Hs

1 856
+ Hs
+ Dm
+ Dm

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Last updated: 15 Jul 2024