HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11685209
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_UBOX
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 667 Hs			1 685
+	Hs
		475753 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476427 TRI36_HUMAN (1-647): 2.78e-95: 311: 24.59		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475297 TRI27_HUMAN (90-433): 1.46e-30: 128: 14.08		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476330 TRIM5_HUMAN (92-376): 2.38e-28: 121: 17.24		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476418 TRI39_HUMAN (1-396): 3.99e-23: 105: 15.40		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475423 TRI23_HUMAN (8-252): 7.45e-19: 92.4: 25.88		UBC_HUMAN (1-685): 0: 846: 100.00
+	Xl
		1186351 NF7B_XENLA (4-261): 4e-19: 93.6: 16.35		Q7SY79_XENLA (77-685): 0: 744: 99.84
+	Hs
		923989 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Hs
		397963 TRI25_HUMAN (4-656): 9.25e-108: 341: 22.80		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Hs
		924042 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Hs
		475200 TRI36_HUMAN (1-647): 2.78e-95: 311: 24.59		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Hs
		398012 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Hs
		1076057 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		OASL_HUMAN (1-153): 6.51e-17: 86.3: 29.11
+	Mm
		476671 RO52_MOUSE (1-262): 3.73e-19: 92.8: 14.59		UBB_MOUSE (457-685): 2.3e-86: 275: 99.56
+	Hs
		734585 TRI23_HUMAN (8-252): 7.45e-19: 92.4: 25.88		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		924236 RO52_MOUSE (1-262): 3.73e-19: 92.8: 14.59		RS27A_MOUSE (609-684): 9.1e-41: 147: 100.00
+	Hs
		475177 TRIM5_HUMAN (92-376): 2.38e-28: 121: 17.24		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Mm
		476831 RO52_MOUSE (1-262): 3.73e-19: 92.8: 14.59		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Rn
		734823 TRI23_RAT (8-252): 1.09e-18: 92: 25.88		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		475134 TRI11_HUMAN (3-249): 9.34e-19: 91.7: 19.03		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70