HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	26748699
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008017 - microtubule binding GO:0034451 - centriolar satellite
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 667 Hs			1 1193
+	Hs
		1300741 TRIM1_HUMAN (1-665): 4.96e-164: 490: 72.81		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		1300728 TRI36_HUMAN (1-647): 2.78e-95: 311: 24.59		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		1171324 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		50964 FSD2_HUMAN (186-661): 6.22e-77: 262: 21.14		SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00
+	Hs
		254493 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		ROCK2_HUMAN (526-1193): 1.76e-21: 103: 11.92
+	Hs
		551749 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		DESP_HUMAN (501-1190): 6.44e-19: 95.8: 11.43
+	Hs
		1067438 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		EEA1_HUMAN (691-1193): 8.44e-18: 91.8: 12.35
+	Hs
		1035181 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		ROCK1_HUMAN (546-1186): 1.44e-17: 90.8: 14.97
+	Hs
		1171050 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		1068580 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		725185 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33
+	Hs
		724888 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		148970 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		528385 TRI63_HUMAN (1-380): 2.91e-86: 276: 24.09		MYH6_HUMAN (958-1190): 3.59e-09: 63.7: 14.16
+	Hs
		149045 CMYA5_HUMAN (160-661): 1.55e-72: 258: 19.63		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Hs
		724822 TRI14_HUMAN (152-652): 3.33e-73: 244: 18.90		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		734810 TRI23_HUMAN (8-252): 7.45e-19: 92.4: 25.88		MYH13_HUMAN (163-961): 2.75e-24: 113: 9.10
+	Hs
		522639 TRIM6_HUMAN (4-290): 3.28e-18: 90.1: 15.63		MYH7_HUMAN (154-896): 6.03e-22: 105: 11.91
+	Hs
		584968 RO52_HUMAN (1-295): 2.16e-18: 90.5: 12.70		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		528393 TRIM6_HUMAN (4-290): 3.28e-18: 90.1: 15.63		MYH6_HUMAN (958-1190): 3.59e-09: 63.7: 14.16