HitPredict

Interactor 1: TRI18 (O15344)
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (Putative transcription factor XPRF) (RING finger protein 59) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)
Gene: MID1

Interactor 2: STK36 (Q9NRP7)
Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)
Gene: STK36

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	25278022
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 1315
+	Hs
		647914 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		MARK3_HUMAN (1-574): 1.67e-139: 445: 20.58
+	Hs
		1183133 TRI36_HUMAN (1-647): 2.78e-95: 311: 24.59		MARK2_HUMAN (1-570): 3.35e-129: 419: 21.95
+	Hs
		1170538 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		MARK2_HUMAN (1-570): 3.35e-129: 419: 21.95
+	Hs
		1057174 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		MELK_HUMAN (1-582): 5e-126: 406: 22.22
+	Hs
		682189 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		AKT2_HUMAN (1-328): 4.09e-126: 400: 28.36
+	Hs
		681909 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		AKT1_HUMAN (1-325): 8.15e-125: 396: 29.43
+	Hs
		1038988 TRI67_HUMAN (54-660): 7.29e-91: 301: 24.39		KCC2G_HUMAN (2-468): 3.25e-122: 392: 24.32
+	Hs
		242816 TRI13_HUMAN (1-97): 1.22e-14: 78.2: 40.21		AKT1_HUMAN (1-325): 8.15e-125: 396: 29.43