Interactor 1: P73 (O15350)
Tumor protein p73 (p53-like transcription factor) (p53-related protein)
Gene: TP73
Interactor 2: P73 (O15350)
Tumor protein p73 (p53-like transcription factor) (p53-related protein)
Gene: TP73
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.87 | 1.00 | 0.933 |
The method score is based on:
Property | Details |
---|---|
Experiments | 9802988, 10961991, 19815500, 22474346, 22340593 |
Identification Methods | two hybrid, x-ray crystallography, mass spectrometry studies of complexes, cosedimentation in solution, cross-linking study, anti tag coimmunoprecipitation, comigration in non denaturing gel electrophoresis |
Interaction Type | direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | P53~P53, P53~P53_tetramer, P53_tetramer~P53_tetramer, SAM_2~SAM_2 |
Common GO terms | GO:0000785 - chromatin GO:0000976 - transcription cis-regulatory region binding GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001222 - transcription corepressor binding and 36 others more... |
Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024