Interactor 1: P73 (O15350)
Tumor protein p73 (p53-like transcription factor) (p53-related protein)
Gene: TP73

Interactor 2: HIPK2 (Q9H2X6)
Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)
Gene: HIPK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.481

The method score is based on:

Property Details
Experiments 11925430
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0042771 - intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0051726 - regulation of cell cycle
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 636
Hs

1 1198
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024