HitPredict

Interactor 1: PPM1G (O15355)
Protein phosphatase 1G (EC 3.1.3.16) (Protein phosphatase 1C) (Protein phosphatase 2C isoform gamma) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma)
Gene: PPM1G

Interactor 2: H2A2B (Q8IUE6)
Histone H2A type 2-B (H2A-clustered histone 21)
Gene: H2AC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	28330616, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 546 Hs			1 130
+	Hs
		176095 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		176104 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62
+	Hs
		176209 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A2A_HUMAN (1-130): 5.07e-68: 202: 94.62
+	Hs
		176256 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A1H_HUMAN (1-128): 7.7e-68: 202: 95.31
+	Hs
		176196 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2A2C_HUMAN (1-127): 3.2e-67: 200: 96.06
+	Hs
		176267 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2AJ_HUMAN (1-127): 5.24e-67: 200: 95.28
+	Hs
		176113 PPM1G_HUMAN (1-546): 5.15e-171: 496: 100.00		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94
+	Hs
		175368 PPM1D_HUMAN (191-508): 3.13e-74: 248: 21.53		H2AX_HUMAN (1-123): 4.57e-66: 198: 95.94
+	Hs
		273452 PPM1B_HUMAN (1-223): 1.14e-54: 193: 21.48		H2A2B_HUMAN (1-130): 2.22e-71: 211: 100.00
+	Hs
		273341 PPM1B_HUMAN (1-223): 1.14e-54: 193: 21.48		H2A1B_HUMAN (1-130): 1e-67: 202: 93.85
+	Hs
		273353 PPM1B_HUMAN (1-223): 1.14e-54: 193: 21.48		H2A1_HUMAN (1-130): 8.04e-68: 202: 94.62