HitPredict

Interactor 1: SHIP2 (O15357)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)
Gene: INPPL1

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0007155 - cell adhesion GO:0006915 - apoptotic process GO:0007015 - actin filament organization
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1258 Hs			1 196
+	Hs
		176425 SHIP2_HUMAN (1-1258): 0: 968: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		925207 OCRL_HUMAN (230-895): 1.35e-168: 526: 19.28		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		915616 OCRL_HUMAN (230-895): 1.35e-168: 526: 19.28		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		892324 OCRL_HUMAN (230-895): 1.35e-168: 526: 19.28		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		120395 OCRL_HUMAN (230-895): 1.35e-168: 526: 19.28		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		166043 SYNJ2_HUMAN (708-1199): 8.8e-10: 65.8: 9.09		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		166039 SYNJ2_HUMAN (708-1199): 8.8e-10: 65.8: 9.09		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54