Interactor 1: SHIP2 (O15357)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)
Gene: INPPL1

Interactor 2: SHIP1 (Q92835)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (EC 3.1.3.86) (Inositol polyphosphate-5-phosphatase D) (EC 3.1.3.56) (Inositol polyphosphate-5-phosphatase of 145 kDa) (SIP-145) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (EC 3.1.3.36) (SH2 domain-containing inositol 5'-phosphatase 1) (SH2 domain-containing inositol phosphatase 1) (SHIP-1) (p150Ship) (hp51CN)
Gene: INPP5D

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19380743
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2
Common GO terms GO:0004445 - inositol-polyphosphate 5-phosphatase activity
GO:0005829 - cytosol
GO:0006661 - phosphatidylinositol biosynthetic process
GO:0006915 - apoptotic process
GO:0017124 - SH3 domain binding
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1258
Hs

1 1189
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024