HitPredict

Interactor 1: EIF3D (O15371)
Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7) (eIF-3-zeta) (eIF3 p66)
Gene: EIF3D

Interactor 2: EIF3I (Q13347)
Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36)
Gene: EIF3I

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 35271311, 24981860, 22190034, 18628297
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains eIF-3_zeta~WD40
Common GO terms GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005852 - eukaryotic translation initiation factor 3 complex
and 5 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 548
Hs

1 325
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024