HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: GATA3 (P23771)
Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3)
Gene: GATA3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.641

The method score is based on:

Property Details
Experiments 29453984, 17075044
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001701 - in utero embryonic development
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006366 - transcription by RNA polymerase II
and 2 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 428
Hs

1 443
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Last updated: 15 Jul 2024