HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: NRIP1 (P48552)
Nuclear receptor-interacting protein 1 (Nuclear factor RIP140) (Receptor-interacting protein 140)
Gene: NRIP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

The method score is based on:

Property	Details
Experiments	17053781, 21868449
Identification Methods	two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000118 - histone deacetylase complex GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm and 4 others more... GO:0005829 - cytosol GO:0032922 - circadian regulation of gene expression GO:0042826 - histone deacetylase binding GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	428
Hs

1	1158

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024