HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: FOXL1 (Q12952)
Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7)
Gene: FOXL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 345
+	Hs
		1021331 HDAC2_HUMAN (3-422): 0: 580: 58.63		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		177261 HDAC3_HUMAN (1-428): 0: 600: 100.00		FOXK2_HUMAN (1-245): 2.81e-51: 182: 32.45
+	Hs
		964178 HDAC1_HUMAN (3-385): 0: 588: 62.92		FOXK2_HUMAN (1-245): 2.81e-51: 182: 32.45
+	Hs
		877628 HDAC2_HUMAN (3-422): 0: 580: 58.63		FOXG1_HUMAN (48-224): 2.13e-52: 182: 40.68
+	Hs
		964220 HDAC2_HUMAN (3-422): 0: 580: 58.63		FOXK2_HUMAN (1-245): 2.81e-51: 182: 32.45
+	Hs
		1038595 HDAC1_HUMAN (3-385): 0: 588: 62.92		FOXJ1_HUMAN (9-249): 1.16e-49: 173: 30.26
+	Hs
		1270410 HDAC2_HUMAN (3-422): 0: 580: 58.63		FOXC2_HUMAN (11-301): 4.93e-52: 181: 32.48
+	Hs
		952807 HDAC1_HUMAN (3-385): 0: 588: 62.92		FOXK1_HUMAN (7-281): 1.72e-46: 169: 29.83
+	Hs
		877999 HDAC2_HUMAN (3-422): 0: 580: 58.63		FOXA3_HUMAN (47-146): 1.57e-50: 173: 63.00
+	Hs
		952845 HDAC2_HUMAN (3-422): 0: 580: 58.63		FOXK1_HUMAN (7-281): 1.72e-46: 169: 29.83
+	Hs
		208927 HDAC2_HUMAN (3-422): 0: 580: 58.63		FOXS1_HUMAN (38-240): 7.82e-49: 168: 41.38
+	Sp
		223482 CLR6_SCHPO (3-403): 0: 541: 57.61		FKH2_SCHPO (12-252): 5.75e-53: 186: 28.63
+	Hs
		1021370 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00