HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: GRDN (Q3V6T2)
Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)
Gene: CCDC88A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 428 Hs			1 1871
+	Hs
		724813 HDAC1_HUMAN (3-385): 0: 588: 62.92		MYH9_HUMAN (1-809): 2.13e-29: 130: 10.02
+	Hs
		724945 HDAC2_HUMAN (3-422): 0: 580: 58.63		MYH9_HUMAN (1-809): 2.13e-29: 130: 10.02
+	Hs
		1038853 HDAC1_HUMAN (3-385): 0: 588: 62.92		MYH4_HUMAN (5-707): 1.9e-26: 121: 12.26
+	Hs
		528410 HDAC1_HUMAN (3-385): 0: 588: 62.92		MYH8_HUMAN (8-679): 1.31e-23: 111: 11.72
+	Hs
		518865 HDAC1_HUMAN (3-385): 0: 588: 62.92		TPR_HUMAN (1125-1868): 4.51e-19: 97: 12.93
+	Hs
		725212 HDAC2_HUMAN (3-422): 0: 580: 58.63		MYH10_HUMAN (43-620): 1.66e-20: 101: 9.86
+	Hs
		148775 HDAC1_HUMAN (3-385): 0: 588: 62.92		CTRO_HUMAN (144-645): 2.42e-16: 88.1: 16.63
+	Hs
		149134 HDAC2_HUMAN (3-422): 0: 580: 58.63		CTRO_HUMAN (144-645): 2.42e-16: 88.1: 16.63
+	Hs
		1038680 HDAC1_HUMAN (3-385): 0: 588: 62.92		CP250_HUMAN (1-682): 8.88e-13: 76.2: 11.44
+	Hs
		1034610 HDAC2_HUMAN (3-422): 0: 580: 58.63		GOGA4_HUMAN (1253-1786): 2.42e-13: 78.1: 7.84
+	Hs
		828581 HDAC1_HUMAN (3-385): 0: 588: 62.92		CENPF_HUMAN (249-1186): 2.54e-10: 68.2: 21.17
+	Hs
		522611 HDAC1_HUMAN (3-385): 0: 588: 62.92		MYH7_HUMAN (1-391): 2.32e-10: 68.1: 12.25
+	Hs
		1038808 HDAC1_HUMAN (3-385): 0: 588: 62.92		MYH2_HUMAN (1-392): 9.18e-09: 63.1: 10.69
+	Hs
		522547 HDAC1_HUMAN (3-385): 0: 588: 62.92		MYH1_HUMAN (1-392): 8.09e-09: 63.1: 10.94
+	Hs
		725053 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		MYH9_HUMAN (1-809): 2.13e-29: 130: 10.02
+	Hs
		728525 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		MYH11_HUMAN (3-722): 1.6e-26: 121: 12.80
+	Mm
		1143175 HDAC6_MOUSE (5-320): 1.83e-105: 338: 23.55		MYH10_MOUSE (4-625): 3.47e-22: 106: 10.69
+	Hs
		725261 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		MYH10_HUMAN (43-620): 1.66e-20: 101: 9.86
+	Hs
		1268107 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		MY18A_HUMAN (599-1309): 1.19e-12: 75.9: 20.46
+	Hs
		551864 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		DESP_HUMAN (244-1208): 1.11e-09: 66.2: 19.09