HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: ZMYM2 (Q9UBW7)
Zinc finger MYM-type protein 2 (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein) (Zinc finger protein 198)
Gene: ZMYM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 32891193
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 1377
+	Hs
		1038779 HDAC1_HUMAN (3-385): 0: 588: 62.92		ZMYM2_HUMAN (1-1377): 0: 1880: 100.00
+	Hs
		1270496 HDAC2_HUMAN (3-422): 0: 580: 58.63		ZMYM2_HUMAN (1-1377): 0: 1880: 100.00
+	Hs
		177295 HDAC3_HUMAN (1-428): 0: 600: 100.00		ZMYM3_HUMAN (175-1377): 0: 1371: 40.96
+	Hs
		1038370 HDAC1_HUMAN (3-385): 0: 588: 62.92		ZMYM3_HUMAN (175-1377): 0: 1371: 40.96
+	Hs
		1051242 HDAC2_HUMAN (3-422): 0: 580: 58.63		ZMYM3_HUMAN (175-1377): 0: 1371: 40.96
+	Hs
		1051267 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		ZMYM3_HUMAN (175-1377): 0: 1371: 40.96
+	Hs
		1131612 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		ZMYM1_HUMAN (534-876): 5.05e-60: 228: 16.44