HitPredict

Interactor 1: SIGL5 (O15389)
Sialic acid-binding Ig-like lectin 5 (Siglec-5) (CD33 antigen-like 2) (Obesity-binding protein 2) (OB-BP2) (OB-binding protein 2) (CD antigen CD170)
Gene: SIGLEC5

Interactor 2: SH21A (O60880)
SH2 domain-containing protein 1A (Duncan disease SH2-protein) (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: SH2D1A

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	19150402
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 551 Hs			1 128
+	Hs
		433947 KIRR1_HUMAN (1-464): 1.32e-49: 184: 17.59		LYN_HUMAN (1-125): 1.04e-39: 140: 19.85
+	Hs
		433742 PTK7_HUMAN (16-532): 4.11e-48: 181: 13.70		LYN_HUMAN (1-125): 1.04e-39: 140: 19.85
+	Mm
		722908 CD22_MOUSE (30-547): 9.12e-47: 177: 17.09		SHIP1_MOUSE (4-103): 9.63e-37: 133: 42.00
+	Hs
		924791 KIRR1_HUMAN (1-464): 1.32e-49: 184: 17.59		GRB2_HUMAN (1-123): 1.97e-35: 122: 19.69
+	Mm
		722901 CD22_MOUSE (30-547): 9.12e-47: 177: 17.09		GRB2_MOUSE (1-123): 1.02e-35: 123: 19.69
+	Hs
		433507 TUTLB_HUMAN (13-451): 4.86e-37: 149: 12.42		YES_HUMAN (1-127): 2.68e-40: 142: 19.40
+	Dm
		219802 O44924_DROME (216-529): 5.28e-37: 149: 12.39		ABL_DROME (1-127): 2.37e-39: 141: 27.82
+	Hs
		434081 TUTLB_HUMAN (13-451): 4.86e-37: 149: 12.42		LYN_HUMAN (1-125): 1.04e-39: 140: 19.85
+	Hs
		523211 TUTLB_HUMAN (13-451): 4.86e-37: 149: 12.42		SRC_HUMAN (1-127): 8.71e-39: 138: 20.90
+	Hs
		412004 MAG_HUMAN (20-549): 8.28e-39: 152: 16.79		FYN_HUMAN (1-125): 4.91e-37: 133: 18.52
+	Hs
		211413 SIGL6_HUMAN (149-551): 8.41e-39: 149: 18.65		SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00
+	Hs
		243162 SIGL7_HUMAN (181-551): 2.78e-34: 137: 20.60		SH21A_HUMAN (1-128): 3.11e-38: 127: 100.00
+	Hs
		522764 CD33_HUMAN (251-549): 3.29e-28: 117: 23.74		SRC_HUMAN (1-127): 8.71e-39: 138: 20.90
+	Hs
		434111 ROBO1_HUMAN (17-550): 7.59e-25: 111: 10.73		LYN_HUMAN (1-125): 1.04e-39: 140: 19.85
+	Mm
		722897 CD22_MOUSE (30-547): 9.12e-47: 177: 17.09		KSYK_MOUSE (5-120): 2.79e-15: 72.8: 24.79
+	Hs
		434019 ROBO2_HUMAN (18-460): 8.51e-21: 99: 12.50		LYN_HUMAN (1-125): 1.04e-39: 140: 19.85
+	Hs
		433249 VCAM1_HUMAN (94-428): 7.72e-19: 92.2: 18.70		YES_HUMAN (1-127): 2.68e-40: 142: 19.40
+	Hs
		155860 ROBO1_HUMAN (17-550): 7.59e-25: 111: 10.73		SH21B_HUMAN (5-119): 1.69e-34: 117: 42.61
+	Hs
		176379 VCAM1_HUMAN (94-428): 7.72e-19: 92.2: 18.70		SHIP2_HUMAN (3-122): 1.12e-34: 128: 37.50
+	Hs
		589563 CD33_HUMAN (251-549): 3.29e-28: 117: 23.74		KSYK_HUMAN (6-120): 2.74e-15: 72.8: 25.86