Interactor 1: TMPS2 (O15393)
Transmembrane protease serine 2 (EC 3.4.21.122) (Serine protease 10) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain]
Gene: TMPRSS2

Interactor 2: ITIH4 (Q14624)
Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4]
Gene: ITIH4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 34709727
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Trypsin~VWA
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0070062 - extracellular exosome
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 492
Hs

1 930
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024