HitPredict

Interactor 1: IPO8 (O15397)
Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)
Gene: IPO8

Interactor 2: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 35271311, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 835
+	Hs
		312256 IPO7_HUMAN (1-1031): 0: 819: 64.57		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		312422 IPO7_HUMAN (1-1031): 0: 819: 64.57		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		668545 XPO2_HUMAN (2-1000): 4.14e-168: 520: 18.06		PML_HUMAN (29-609): 1.21e-57: 214: 14.00
+	Hs
		874613 XPO2_HUMAN (2-1000): 4.14e-168: 520: 18.06		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		1273242 TNPO1_HUMAN (12-883): 1.02e-146: 462: 12.75		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		155633 TNPO2_HUMAN (12-883): 9.66e-136: 433: 12.21		TRIM8_HUMAN (59-589): 2.74e-56: 205: 16.09
+	Hs
		1299145 IPO9_HUMAN (4-994): 3.76e-119: 393: 14.41		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		262175 IMB1_HUMAN (5-859): 6.55e-113: 371: 12.47		TRIM3_HUMAN (122-628): 2.47e-53: 200: 15.85