HitPredict

Interactor 1: IPO8 (O15397)
Importin-8 (Imp8) (Ran-binding protein 8) (RanBP8)
Gene: IPO8

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1037 Hs			1 768
+	Hs
		312262 IPO7_HUMAN (1-1031): 0: 819: 64.57		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		874505 XPO2_HUMAN (2-1000): 4.14e-168: 520: 18.06		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042209 TNPO1_HUMAN (12-883): 1.02e-146: 462: 12.75		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		155572 TNPO2_HUMAN (12-883): 9.66e-136: 433: 12.21		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042784 IPO11_HUMAN (1-996): 3.31e-122: 399: 16.09		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042320 IPO9_HUMAN (4-994): 3.76e-119: 393: 14.41		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041594 IMB1_HUMAN (5-859): 6.55e-113: 371: 12.47		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1043171 IPO9_HUMAN (4-994): 3.76e-119: 393: 14.41		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1042989 IMB1_HUMAN (5-859): 6.55e-113: 371: 12.47		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043355 IMB1_HUMAN (5-859): 6.55e-113: 371: 12.47		CUL4B_HUMAN (5-768): 0: 779: 36.77