HitPredict

Interactor 1: FOXP2 (O15409)
Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat-containing gene 10 protein)
Gene: FOXP2

Interactor 2: ZFHX4 (Q86UP3)
Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4)
Gene: ZFHX4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29365100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 715 Hs			1 3567
+	Hs
		1199931 FOXP1_HUMAN (1-715): 9.87e-133: 409: 60.06		ZFHX4_HUMAN (1-3567): 0: 1729: 95.83
+	Hs
		1199918 FOXP4_HUMAN (1-704): 4.54e-116: 366: 48.81		ZFHX4_HUMAN (1-3567): 0: 1729: 95.83
+	Hs
		1021229 FOXI1_HUMAN (369-698): 4.94e-54: 192: 19.02		ZFHX4_HUMAN (1-3567): 0: 1729: 95.83
+	Hs
		1021312 FOXL1_HUMAN (501-693): 9.52e-42: 157: 24.04		ZFHX4_HUMAN (1-3567): 0: 1729: 95.83
+	Hs
		1199934 FOXJ2_HUMAN (502-576): 4.16e-12: 71.2: 45.00		ZFHX4_HUMAN (1-3567): 0: 1729: 95.83
+	Hs
		822647 FOXP4_HUMAN (1-704): 4.54e-116: 366: 48.81		LHX1_HUMAN (2539-2624): 7.55e-09: 63.2: 42.86
+	Hs
		175972 FOXN1_HUMAN (241-699): 1.03e-60: 217: 18.63		LHX8_HUMAN (2085-2165): 6.66e-10: 65.9: 38.27
+	Hs
		822650 KMT2C_HUMAN (136-508): 1.94e-51: 196: 16.84		LHX1_HUMAN (2539-2624): 7.55e-09: 63.2: 42.86
+	Hs
		822694 FOXA2_HUMAN (405-705): 1.47e-50: 184: 17.56		LHX1_HUMAN (2539-2624): 7.55e-09: 63.2: 42.86
+	Hs
		1021292 FOXL1_HUMAN (501-693): 9.52e-42: 157: 24.04		ZFHX3_HUMAN (1632-3519): 2.55e-12: 75.8: 8.58