Interactor 1: MRP4 (O15439)
ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4)
Gene: ABCC4

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 18045536
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_membrane~ABC_membrane, ABC_membrane~ABC_tran, ABC_membrane~CFTR_R, ABC_tran~ABC_tran, ABC_tran~CFTR_R
Common GO terms GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0016324 - apical plasma membrane
GO:0016887 - ATP hydrolysis activity
and 4 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1325
Hs

1 1480
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Hs
+ Rn

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Last updated: 15 Jul 2024