HitPredict

Interactor 1: MRP4 (O15439)
ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4)
Gene: ABCC4

Interactor 2: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1325 Hs			1 250
+	Hs
		119023 MRP4_HUMAN (1-1325): 0: 1077: 100.00		LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67
+	Hs
		121056 MRP4_HUMAN (1-1325): 0: 1077: 100.00		LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11
+	Hs
		179360 MRP4_HUMAN (1-1325): 0: 1077: 100.00		LEG9B_HUMAN (108-249): 5.78e-38: 137: 37.67
+	Hs
		179365 MRP4_HUMAN (1-1325): 0: 1077: 100.00		LEG9C_HUMAN (108-249): 6.7e-38: 137: 37.67
+	Hs
		119024 MRP5_HUMAN (11-1279): 0: 863: 32.69		LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67
+	Hs
		437179 MDR1_HUMAN (38-634): 3.21e-111: 382: 19.84		LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00
+	Hs
		119094 MDR1_HUMAN (38-634): 3.21e-111: 382: 19.84		LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67
+	Hs
		437194 MDR1_HUMAN (38-634): 3.21e-111: 382: 19.84		LEG9B_HUMAN (108-249): 5.78e-38: 137: 37.67
+	Hs
		572294 MRP1_HUMAN (652-1287): 2.73e-59: 226: 15.89		LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00
+	Hs
		572423 MRP2_HUMAN (621-1294): 4.63e-56: 216: 16.11		LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00
+	Hs
		119206 MRP1_HUMAN (652-1287): 2.73e-59: 226: 15.89		LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67
+	Hs
		121117 MRP1_HUMAN (652-1287): 2.73e-59: 226: 15.89		LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11
+	Hs
		119468 MRP2_HUMAN (621-1294): 4.63e-56: 216: 16.11		LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67