HitPredict

Interactor 1: MRP5 (O15440)
ATP-binding cassette sub-family C member 5 (EC 7.6.2.-) (EC 7.6.2.2) (Multi-specific organic anion transporter C) (MOAT-C) (Multidrug resistance-associated protein 5) (SMRP) (pABC11)
Gene: ABCC5

Interactor 2: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1437 Hs			1 193
+	Hs
		179403 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		179406 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		179408 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		179401 MRP5_HUMAN (1-1437): 0: 1065: 100.00		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		179393 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		179405 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		179400 MRP5_HUMAN (1-1437): 0: 1065: 100.00		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Hs
		706695 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		706702 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		436176 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00
+	Hs
		706705 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		706693 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		545225 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		706700 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		706692 MRP1_HUMAN (20-780): 2.76e-71: 265: 15.01		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Sc
		419697 YCFI_YEAST (20-790): 5.11e-45: 181: 13.45		RHO1_YEAST (3-179): 1.62e-95: 278: 74.01