HitPredict

Interactor 1: RPA34 (O15446)
DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (DNA-directed RNA polymerase I subunit G) (RNA polymerase I-associated factor PAF49)
Gene: POLR1G

Interactor 2: NSD2 (O96028)
Histone-lysine N-methyltransferase NSD2 (EC 2.1.1.357) (Multiple myeloma SET domain-containing protein) (MMSET) (Nuclear SET domain-containing protein 2) (Protein trithorax-5) (Wolf-Hirschhorn syndrome candidate 1 protein)
Gene: NSD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 510 Hs			1 1365
+	Hs
		331865 CHAP1_HUMAN (52-504): 3.38e-12: 71.2: 12.14		NSD2_HUMAN (1-1365): 0: 980: 100.00
+	Hs
		331812 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		NSD2_HUMAN (1-1365): 0: 980: 100.00
+	Hs
		179804 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		NSD3_HUMAN (116-1340): 0: 758: 45.19
+	Hs
		179824 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		EHMT1_HUMAN (906-1224): 5.39e-55: 212: 21.43
+	Hs
		179610 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		KMT2A_HUMAN (1049-1203): 7.37e-42: 171: 32.05
+	Hs
		179884 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		KMT2B_HUMAN (1049-1203): 1.21e-41: 170: 32.05
+	Hs
		179778 RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00		NSD1_HUMAN (69-658): 1.83e-25: 117: 14.33
+	Hs
		1295406 CHAP1_HUMAN (52-504): 3.38e-12: 71.2: 12.14		EHMT1_HUMAN (906-1224): 5.39e-55: 212: 21.43
+	Hs
		1295391 CHAP1_HUMAN (52-504): 3.38e-12: 71.2: 12.14		EHMT2_HUMAN (889-1199): 3.73e-54: 209: 20.65
+	Hs
		1056971 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		SETD2_HUMAN (852-1238): 1.1e-53: 209: 27.74
+	Hs
		975294 TITIN_HUMAN (60-509): 8.33e-09: 60.8: 10.21		KMT2A_HUMAN (1049-1203): 7.37e-42: 171: 32.05
+	Dm
		332876 Q9VPR2_DROME (63-508): 6.41e-26: 113: 11.60		CHDM_DROME (1238-1285): 6.78e-12: 72.7: 42.00
+	Hs
		1056940 MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54		NSD1_HUMAN (69-658): 1.83e-25: 117: 14.33