Interactor 1: RPA34 (O15446)
DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (DNA-directed RNA polymerase I subunit G) (RNA polymerase I-associated factor PAF49)
Gene: POLR1G

Interactor 2: RPA49 (Q9GZS1)
DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53)
Gene: POLR1E

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.90 0.850

The method score is based on:

Property Details
Experiments 15226435, 24981860, 34079125, 35271311
Identification Methods far western blotting, affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_polI_A34~RNA_pol_I_A49
Common GO terms GO:0001650 - fibrillar center
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005736 - RNA polymerase I complex
GO:0006361 - transcription initiation at RNA polymerase I promoter
Homologous interactions 0

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Last updated: 15 Jul 2024