Interactor 1: TLR3 (O15455)
Toll-like receptor 3 (CD antigen CD283)
Gene: TLR3

Interactor 2: IRF1 (P10914)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 12672806, 21220691
Identification Methods electrophoretic mobility supershift assay, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0032728 - positive regulation of interferon-beta production
GO:0032735 - positive regulation of interleukin-12 production
GO:0035458 - cellular response to interferon-beta
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 904
Hs

1 325
+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024