Interactor 1: MSH4 (O15457)
MutS protein homolog 4 (hMSH4)
Gene: MSH4

Interactor 2: MLH1 (P40692)
DNA mismatch repair protein Mlh1 (MutL protein homolog 1)
Gene: MLH1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.812

The method score is based on:

Property Details
Experiments 10928988, 32814904
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~MutS_II, HATPase_c_3~MutS_III, HATPase_c_3~MutS_V
Common GO terms GO:0000795 - synaptonemal complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005694 - chromosome
GO:0006298 - mismatch repair
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 936
Hs

1 756
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Ec
+ Sc
+ Sc
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024