HitPredict

Interactor 1: MAGB4 (O15481)
Melanoma-associated antigen B4 (MAGE-B4 antigen)
Gene: MAGEB4

Interactor 2: MAGA3 (P43357)
Melanoma-associated antigen 3 (Antigen MZ2-D) (Cancer/testis antigen 1.3) (CT1.3) (MAGE-3 antigen)
Gene: MAGEA3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28401488
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MAGE~MAGE
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 314
+	Hs
		796255 MAGAB_HUMAN (1-313): 8.1e-148: 425: 44.16		MAGAB_HUMAN (1-314): 2.21e-154: 440: 59.62
+	Hs
		180538 MAGB4_HUMAN (1-346): 6.68e-154: 437: 100.00		MAGA8_HUMAN (1-313): 3.22e-147: 418: 63.29
+	Hs
		795849 MAGAB_HUMAN (1-313): 8.1e-148: 425: 44.16		MAGA6_HUMAN (1-314): 3.52e-149: 423: 95.86
+	Hs
		180536 MAGB4_HUMAN (1-346): 6.68e-154: 437: 100.00		MAGA1_HUMAN (1-303): 3.01e-138: 395: 67.00
+	Hs
		795807 MAGAA_HUMAN (1-321): 6.21e-140: 403: 44.38		MAGA4_HUMAN (1-304): 5.82e-150: 425: 68.85
+	Hs
		795805 MAGA8_HUMAN (1-312): 1.68e-140: 402: 43.04		MAGA4_HUMAN (1-304): 5.82e-150: 425: 68.85
+	Hs
		180525 MAGB4_HUMAN (1-346): 6.68e-154: 437: 100.00		MAGB4_HUMAN (1-314): 3.93e-135: 388: 39.17
+	Hs
		795715 MAGA3_HUMAN (1-313): 1.18e-140: 402: 39.17		MAGA6_HUMAN (1-314): 3.52e-149: 423: 95.86
+	Hs
		795716 MAGA3_HUMAN (1-313): 1.18e-140: 402: 39.17		MAGA8_HUMAN (1-313): 3.22e-147: 418: 63.29
+	Hs
		180569 MAGB4_HUMAN (1-346): 6.68e-154: 437: 100.00		MAGBA_HUMAN (1-311): 2.99e-132: 381: 37.58
+	Hs
		795688 MAGA3_HUMAN (1-313): 1.18e-140: 402: 39.17		MAGA2_HUMAN (1-314): 2.11e-143: 408: 84.40
+	Hs
		180521 MAGB3_HUMAN (1-344): 2.94e-143: 410: 55.46		MAGA1_HUMAN (1-303): 3.01e-138: 395: 67.00
+	Hs
		796054 MAGAA_HUMAN (1-321): 6.21e-140: 403: 44.38		MAGA9_HUMAN (1-314): 4.46e-136: 389: 58.36
+	Hs
		796241 MAGAA_HUMAN (1-321): 6.21e-140: 403: 44.38		MAGBA_HUMAN (1-311): 2.99e-132: 381: 37.58
+	Hs
		180169 MAGB4_HUMAN (1-346): 6.68e-154: 437: 100.00		MAGB2_HUMAN (1-314): 1.02e-118: 345: 36.79
+	Hs
		56489 MAGA4_HUMAN (1-303): 1.41e-136: 392: 40.00		MAGBG_HUMAN (1-314): 3.56e-134: 385: 41.20
+	Hs
		1297544 MAGBI_HUMAN (1-312): 6.11e-137: 394: 53.48		MAGBA_HUMAN (1-311): 2.99e-132: 381: 37.58