HitPredict

Interactor 1: MAGB4 (O15481)
Melanoma-associated antigen B4 (MAGE-B4 antigen)
Gene: MAGEB4

Interactor 2: MAGA8 (P43361)
Melanoma-associated antigen 8 (Cancer/testis antigen 1.8) (CT1.8) (MAGE-8 antigen)
Gene: MAGEA8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.740

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	MAGE~MAGE
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 318
+	Hs
		796255 MAGAB_HUMAN (1-313): 8.1e-148: 425: 44.16		MAGAB_HUMAN (1-315): 4.31e-161: 457: 60.64
+	Hs
		180537 MAGB4_HUMAN (1-346): 6.68e-154: 437: 100.00		MAGA3_HUMAN (1-316): 1.13e-152: 432: 63.29
+	Hs
		795716 MAGA3_HUMAN (1-313): 1.18e-140: 402: 39.17		MAGA8_HUMAN (1-318): 6.31e-158: 445: 100.00
+	Hs
		180525 MAGB4_HUMAN (1-346): 6.68e-154: 437: 100.00		MAGB4_HUMAN (1-316): 1.29e-140: 402: 42.72
+	Hs
		795849 MAGAB_HUMAN (1-313): 8.1e-148: 425: 44.16		MAGA6_HUMAN (1-316): 1.58e-145: 414: 63.29
+	Hs
		180569 MAGB4_HUMAN (1-346): 6.68e-154: 437: 100.00		MAGBA_HUMAN (1-314): 2.54e-138: 397: 42.99
+	Hs
		180536 MAGB4_HUMAN (1-346): 6.68e-154: 437: 100.00		MAGA1_HUMAN (1-306): 1.04e-138: 396: 67.32
+	Hs
		795807 MAGAA_HUMAN (1-321): 6.21e-140: 403: 44.38		MAGA4_HUMAN (1-307): 1.85e-151: 429: 72.08
+	Hs
		795805 MAGA8_HUMAN (1-312): 1.68e-140: 402: 43.04		MAGA4_HUMAN (1-307): 1.85e-151: 429: 72.08
+	Hs
		795715 MAGA3_HUMAN (1-313): 1.18e-140: 402: 39.17		MAGA6_HUMAN (1-316): 1.58e-145: 414: 63.29
+	Hs
		795688 MAGA3_HUMAN (1-313): 1.18e-140: 402: 39.17		MAGA2_HUMAN (1-316): 2.39e-142: 405: 63.29
+	Hs
		180521 MAGB3_HUMAN (1-344): 2.94e-143: 410: 55.46		MAGA1_HUMAN (1-306): 1.04e-138: 396: 67.32
+	Hs
		796054 MAGAA_HUMAN (1-321): 6.21e-140: 403: 44.38		MAGA9_HUMAN (1-316): 1.44e-139: 399: 66.46
+	Hs
		796241 MAGAA_HUMAN (1-321): 6.21e-140: 403: 44.38		MAGBA_HUMAN (1-314): 2.54e-138: 397: 42.99
+	Hs
		1297544 MAGBI_HUMAN (1-312): 6.11e-137: 394: 53.48		MAGBA_HUMAN (1-314): 2.54e-138: 397: 42.99
+	Hs
		180169 MAGB4_HUMAN (1-346): 6.68e-154: 437: 100.00		MAGB2_HUMAN (1-316): 2.71e-120: 350: 40.06
+	Hs
		56489 MAGA4_HUMAN (1-303): 1.41e-136: 392: 40.00		MAGBG_HUMAN (1-316): 3.16e-136: 390: 45.74