HitPredict

Interactor 1: INSI1 (O15503)
Insulin-induced gene 1 protein (INSIG-1)
Gene: INSIG1

Interactor 2: ERLN2 (O94905)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: ERLIN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	32322062, 21343306, 22690709, 24217618
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0032933 - SREBP signaling pathway GO:0045717 - negative regulation of fatty acid biosynthetic process
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 277 Hs			1 339
+	Hs
		181019 INSI1_HUMAN (1-277): 5.56e-175: 485: 100.00		ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03