Interactor 1: INSI1 (O15503)
Insulin-induced gene 1 protein (INSIG-1)
Gene: INSIG1
Interactor 2: HMDH (P04035)
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34)
Gene: HMGCR
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.86 | 1.00 | 0.931 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | INSIG~Sterol-sensing |
| Common GO terms | GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0006695 - cholesterol biosynthetic process |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
