Interactor 1: ARPC5 (O15511)
Actin-related protein 2/3 complex subunit 5 (Arp2/3 complex 16 kDa subunit) (p16-ARC)
Gene: ARPC5

Interactor 2: ARPC4 (P59998)
Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC)
Gene: ARPC4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 11162547, 12451597, 33961781, 37071682, 24981860, 35235311, 34349018, 26655834
Identification Methods two hybrid, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ARPC4~P16-Arc
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
GO:0034314 - Arp2/3 complex-mediated actin nucleation
and 3 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 151
Hs

1 168
+ Dm
+ Hs
+ Sp
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024