HitPredict

Interactor 1: RPB4 (O15514)
DNA-directed RNA polymerase II subunit RPB4 (RNA polymerase II subunit B4) (DNA-directed RNA polymerase II subunit D) (RNA polymerase II 16 kDa subunit) (RPB16)
Gene: POLR2D

Interactor 2: RPB11 (P52435)
DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit)
Gene: POLR2J

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.736

Property	Details
Experiments	28514442, 24981860, 33961781, 35271311, 17643375, 15282305
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 117
+	Hs
		181451 RPB4_HUMAN (1-142): 4e-59: 181: 100.00		RPB1B_HUMAN (1-109): 7.3e-48: 150: 95.41
+	Sc
		593063 RPB4_YEAST (42-140): 3.4e-27: 102: 35.58		RPB11_YEAST (1-110): 4.2e-45: 144: 50.00