HitPredict

Interactor 1: CFLAR (O15519)
CASP8 and FADD-like apoptosis regulator (Caspase homolog) (CASH) (Caspase-eight-related protein) (Casper) (Caspase-like apoptosis regulatory protein) (CLARP) (Cellular FLICE-like inhibitory protein) (c-FLIP) (FADD-like antiapoptotic molecule 1) (FLAME-1) (Inhibitor of FLICE) (I-FLICE) (MACH-related inducer of toxicity) (MRIT) (Usurpin) [Cleaved into: CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12]
Gene: CFLAR

Interactor 2: Q9BPW0 (Q9BPW0)
Serine/threonine-protein phosphatase (EC 3.1.3.16)
Gene: PPP5C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 484
+	Hs
		930848 CASP8_HUMAN (6-478): 8.27e-152: 442: 24.85		PP2AA_HUMAN (188-483): 3.01e-169: 480: 40.33
+	Xl
		738158 Q9IB67_XENLA (79-479): 8.51e-104: 318: 17.67		PP1GA_XENLA (195-481): 1.85e-152: 438: 37.85
+	Hs
		788178 CASP3_HUMAN (209-479): 8.43e-89: 274: 22.53		PP2AA_HUMAN (188-483): 3.01e-169: 480: 40.33