HitPredict

Interactor 1: FGF10 (O15520)
Fibroblast growth factor 10 (FGF-10) (Keratinocyte growth factor 2)
Gene: FGF10

Interactor 2: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.874

The method score is based on:

Property Details
Experiments 18199118, 9582367, 10339576, 12591959
Identification Methods unspecified method, pull down, affinity chromatography technology, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FGF~I-set, FGF~Ig_3
Common GO terms GO:0001525 - angiogenesis
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
and 23 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 208
Hs

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Last updated: 15 Jul 2024