HitPredict

Interactor 1: SOCS1 (O15524)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3)
Gene: SOCS1

Interactor 2: TBG1 (P23258)
Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1)
Gene: TUBG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29991678, 15456882
Identification Methods	affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 451
+	Hs
		181767 SOCS1_HUMAN (1-211): 6.15e-51: 165: 100.00		TBB5_HUMAN (3-439): 0: 652: 33.79
+	Hs
		181840 SOCS1_HUMAN (1-211): 6.15e-51: 165: 100.00		TBB4B_HUMAN (3-437): 0: 651: 33.95
+	Hs
		181757 SOCS1_HUMAN (1-211): 6.15e-51: 165: 100.00		TBB4A_HUMAN (3-437): 0: 650: 33.49
+	Hs
		147507 SOCS6_HUMAN (66-209): 1.11e-39: 144: 26.06		TBB4B_HUMAN (3-437): 0: 651: 33.95
+	Hs
		411549 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TBB5_HUMAN (3-439): 0: 652: 33.79
+	Hs
		411668 LCK_HUMAN (4-194): 3.94e-39: 142: 13.46		TBB4B_HUMAN (3-437): 0: 651: 33.95
+	Hs
		924548 GRB2_HUMAN (52-181): 4.7e-36: 127: 16.79		TBB3_HUMAN (3-451): 0: 653: 33.11
+	Hs
		428131 GRB2_HUMAN (52-181): 4.7e-36: 127: 16.79		TBB5_HUMAN (3-439): 0: 652: 33.79
+	Hs
		924460 GRB2_HUMAN (52-181): 4.7e-36: 127: 16.79		TBB4B_HUMAN (3-437): 0: 651: 33.95
+	Hs
		924827 GRB2_HUMAN (52-181): 4.7e-36: 127: 16.79		TBA1C_HUMAN (3-451): 0: 651: 30.85
+	Hs
		924458 GRB2_HUMAN (52-181): 4.7e-36: 127: 16.79		TBA1B_HUMAN (3-442): 0: 649: 31.25
+	Hs
		924836 GRB2_HUMAN (52-181): 4.7e-36: 127: 16.79		TBB6_HUMAN (3-442): 0: 649: 33.56
+	Hs
		129166 P85B_HUMAN (75-174): 7.87e-18: 82.9: 25.00		TBB5_HUMAN (3-439): 0: 652: 33.79
+	Hs
		129329 P85B_HUMAN (75-174): 7.87e-18: 82.9: 25.00		TBA1C_HUMAN (3-451): 0: 651: 30.85
+	Hs
		129330 P85B_HUMAN (75-174): 7.87e-18: 82.9: 25.00		TBB6_HUMAN (3-442): 0: 649: 33.56
+	Hs
		655312 P85A_HUMAN (57-180): 1.73e-17: 82.1: 20.64		TBA1B_HUMAN (3-442): 0: 649: 31.25